More research needed to better discern differences in graft-versus-host disease, dry eye


Ocular Graft-versus-host disease (GVHD) is a severe form of dry eye disease that extends beyond traditional classifications. Similar to DED, there is no consensus on measuring ocular GVHD. Symptoms include burning, foreign body sensation, and decreased vision. Treatment involves relieving symptoms and minimizing inflammation using corticosteroids, cyclosporine, tacrolimus, or autologous serum tears. Management may include punctal plugs, scleral contact lenses, autologous serum, or amniotic membrane. Understanding the etiology and developing a treatment plan targeting multiple ocular structures concurrently is key to success. This comprehensive overview emphasizes the need for greater understanding of this challenging condition.

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