Suppressive antibiotics for periprosthetic joint infection; bird flu updates


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A 12-week course of suppressive antibiotic therapy for periprosthetic joint infections did not show an overall benefit, but it may be more effective among patients in the United States who have higher treatment failure rates, data show.

“The decision to prescribe long-term suppressive antibiotics should be made carefully, taking into account each individual patient’s specific characteristics and risk factors,” Don Bambino Geno Tai, MD, MBA, an assistant professor of medicine in the division of infectious diseases and international medicine at the University of Minnesota Medical School, told Healio.





Six more dairy cattle herds in the United States have tested positive for avian influenza. Image: Adobe Stock

It was the top story in infectious disease last week.

The second top story was about updates on the “bird flu” outbreak among cattle in the U.S. Health officials said that six more herds of dairy cattle tested positive for H5N1, raising the total number of infected herds nationwide to 42. The CDC is recommending that farm workers in the affected states wear personal protective equipment.

Read these and more top stories in infectious diseases below:

Suppressive antibiotics beneficial only for some patients with PJI

Despite suppressive antibiotic therapy being a routine strategy for managing periprosthetic joint infections, a study showed the benefits may be limited. Read more.

Bird flu updates: Six more cattle herds test positive

Six more dairy cattle herds in the United States have tested positive for avian influenza, bringing the national total to 42 herds, according to the U.S. Department of Agriculture. Read more.

Q&A: Should the US be testing more for bird flu?

H5N1 “bird flu” is widespread among wild birds and has caused sporadic outbreaks among poultry for more than a couple years. A recent outbreak among dairy cow herds in the United States has raised the virus’ profile. Read more.

Three more countries eliminate congenital HIV, syphilis

Belize, Jamaica and St. Vincent and the Grenadines became the latest nations to eliminate mother-to-child transmission of HIV and syphilis, the Pan American Health Organization announced. Read more.

Standard infection control prevented C. auris spread in dialysis facility

Standard infection prevention and control procedures prevented the spread of Candida auris at a Tennessee dialysis facility despite two patients there being colonized for up to 4 months during treatment, researchers reported. Read more.

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