Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain specialized structures called organelles, crucial for cell function and linked to diseases if dysfunctional. Researchers at the University of Geneva used high-resolution microscopy and kinematic techniques to visualize the genesis of the centriole, important for cell organization. This study, published in Cell, sheds light on centriole assembly complexities and offers new avenues for organelle study. Expansion microscopy allowed for detailed observation of centriole proteins, leading to a reconstruction of centriole assembly stages. This innovative approach provides insights into organelle formation and has the potential for broader applications in cellular and molecular biology.

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