Regular late-life exercise has a beneficial impact on DNA damage and telomere dysfunction

A new study presented at the American Physiology Summit shows that regular aerobic exercise later in life can prevent DNA damage and telomere dysfunction, improving vascular health. Previous studies indicated that aerobic exercise in older individuals reduces the risk of cardiovascular disease-related mortality. This study focused on how exercise impacts genomic stability, particularly in endothelial cells that come in contact with blood flow. The study involved 15 male mice engaging in different levels of exercise for four months, showing that increased aerobic exercise later in life can have a positive effect on DNA damage and telomere dysfunction, potentially improving cardiovascular health in humans.

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