Higher Mortality in Men With Chronic Airway Obstruction, Restrictive Spirometry

A study found that patients with chronic airway obstruction (CAO) and restrictive spirometry pattern (RSP) have a higher risk of all-cause mortality compared to those with normal lung function (NLF), with men with CAO having the highest risk. The study involved 1986 individuals and showed that CAO was associated with respiratory death in women and cardiovascular death in men, while RSP was associated with respiratory death in both sexes. Cardiovascular mortality was the most common cause of death in all groups. The study found increased hazard ratios for all-cause mortality in the CAO and RSP groups compared to the NLF group, with men having higher risks than women. Limitations included low statistical power for RSP and only baseline spirometry data being analyzed.

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