Gait Limitations Prior to auto-HCT Prompt Worse Perceived Functional Outcomes

Patients with gait limitations before autologous hematopoietic cell transplant (auto-HCT) were more likely to have worse functional limitations after the transplant, according to a study published in Archives of Physical Medicine and Rehabilitation. The study included 101 patients undergoing auto-HCT for lymphatic or hematopoietic malignancy. Mobility assessments using inertial sensors showed a decline in mobility pre-engraftment, with gait limitations pretransplant associated with lower perceived function postengraftment. Early intervention during the pre-engraftment period may help prevent further mobility declines and improve recovery. However, the study had limitations, including not including patients too ill to complete mobility assessments.

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