Understanding giggle incontinence: Causes, symptoms, and management

Giggle incontinence is a rare bladder storage disorder characterized by uncontrollable urine loss during laughter episodes. Historically mistaken for stress urinary incontinence, giggle incontinence is different and affects primarily females over five years old. Pathophysiology involves central nervous system dysfunction, with links to cataplexy and ADHD. Diagnosis includes voiding history, physical exams, and urodynamic studies. Treatments include standard urotherapy, biofeedback, and methylphenidate, with moderate success rates. Biofeedback has shown efficacy in 73% of patients, while methylphenidate can completely resolve symptoms but may cause adverse effects. Understanding giggle incontinence is crucial for accurate diagnosis and appropriate treatment.

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