Target These Serum Urate Levels to Prevent Gout Flares


A study published in the JAMA tracked 3613 gout patients aged 40-69 and found that aiming for serum urate levels of less than 5 or 6 mg/dL could prevent a majority of gout flares and hospitalizations. The study was conducted from 2006-2010 to 2017 or 2020 among 86% men. The study showed that patients with baseline SU levels below 6.0 mg/dL had an acute gout flare rate of 10.6 per 1000 person-years. Another study from 2021 and 2022 also linked reductions in SU to less than 6 md/dL to lower flare rates. This suggests that a treat-to-target strategy may be best for treating gout.

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