Skin Manifestations of Systemic Cancers

Dermatologists play an important role in identifying and detecting various types of cancer before they reach later stages. Paraneoplastic diseases are clinical disorders that manifest in association with underlying malignancies. Dermatologists can help identify these diseases based on specific criteria, and they play a significant role in the early detection of internal malignancies. Cutaneous lesions are often associated with cancers and indicate the presence of an underlying malignancy. Understanding these manifestations can improve treatment outcomes for associated cancers. Various skin conditions, such as Acanthosis Nigricans, Erythema Gyratum Repens, Leser-Trélat Sign, Necrolytic Migratory Erythema, Paraneoplastic Pemphigus, and Sweet’s Syndrome are important clinical markers for early cancer detection and improved outcomes.

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