Why Do DMARDs Take Time to Work for RA?

Disease-modifying antirheumatic drugs (DMARDs) are used to treat rheumatoid arthritis (RA), but the time it takes for them to be fully effective varies depending on the type used. They target inflammation and work with the immune system to slow down or stop the disease, ultimately minimizing joint damage. Common conventional and biologic DMARDs used for RA include methotrexate, sulfasalazine, hydroxychloroquine, and biologic DMARD drugs, such as infliximab. While success varies, the main goal is to reach remission, and it is common to try multiple DMARDs until you find the best one. Once the right medication is found, you may need to take it indefinitely to control this lifelong disease.

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