Substance Abuse Ups DKA Readmission Risk in Type 1 Diabetes

A study conducted at a large county hospital in Texas found significant associations between readmission with diabetic ketoacidosis (DKA) in people with type 1 diabetes (T1D) and both substance abuse and incarceration. The study identified 243 T1D patients admitted with a DKA diagnosis, with 64 having multiple admissions. Substance use disorder was identified in 40.3% of patients, with significantly higher rates in those with multiple DKA admissions. Cannabis use remained independently associated with a significantly increased odds of DKA readmission. Patients with multiple DKA admissions were also more likely to have a history of incarceration. The findings suggest a need for interventions to decrease recurrence of DKA episodes in similar hospital populations. The study was conducted by Josh Peedikayil, MD, and colleagues and was published in the Journal of the Endocrine Society. Limitations include the single center nature of the study, limited time period, potential for inaccuracies in chart data, and unknown precipitants of DKA. The study received no funding.

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