Opioid prescriptions are common in NP.
Despite decline over time, 1 in 4 patients remain on opioids at disease resolution.
These data identify an opportunity to adjust analgesic prescription practice in NP
Rates of opioid usage during necrotizing pancreatitis (NP) disease course are unknown.
We hypothesized that a significant number of NP patients were prescribed opioid analgesics
Single institution IRB-approved retrospective study of 230 NP patients treated between
2015 and 2019.
Data were available for 198/230 (86%) patients. 166/198 (84%) were discharged from
their index hospitalization with a prescription for an opioid. At the first clinic
visit following hospitalization, 110/182 (60%) were using opioids. Six months after
disease onset, 72/163 (44%) continued to require opioids. At disease resolution, 38/144
(26%) patients remained on opioid medications. The rate of active opioid prescriptions
at six months after disease onset declined throughout the period studied from 68%
in 2015 to 39% in 2019.
Opioid prescriptions are common in NP. Despite decline over time, 1 in 4 patients
remain on opioids at disease resolution. These data identify an opportunity to adjust
analgesic prescription practice in NP patients.
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