In textbooks, diagrams of the inside of the cell don’t show the full picture. The cell’s interior is a dynamic place, with millions of molecules and organelles jostling around. And the placement of the cell’s nucleus at any given time can hold information about what the cell is going through, because it is key for many cellular functions. In fact, none of us would be alive if not for nuclear movement during fertilization of an egg cell.
Edgar Gomes of Universidade de Lisboa wants to know how the position of the nucleus contributes to the functioning of the cell and tissue. As a third time Whitman Fellow at MBL and first time Nikon Fellow, Gomes is no stranger to the campus. Over the last three years, he has built a robust research program using skeletal muscle cells to investigate nuclear positioning and movement within the cell.