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Response to: Correspondence on 'Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation does need confirmation' by Armoiry and Connock


The Authors’ reply: We read with interest the response of Armoiry and Connock to our editorial1 and to the Cohen et al paper2 it referred to. This response demonstrates the wide interest on cost-effectiveness of transcatheter edge-to-edge repair (TEER) in secondary mitral regurgitation. Armoiry and Connock generously conclude that the paper by Cohen et al ‘represents a valuable contribution’, although criticising it throughout the text. Regarding our editorial, we are sorry that Armoiry and Connock disagree with our statement that cost-effectiveness of TEER in secondary mitral regurgitation does not need confirmation. Yet, our statement refers strictly to the UK NHS and is underpinned by the cost-effectiveness analyses that informed the National Institute for Health and Care Excellence (NICE) guidelines recommendation3: the NICE MitraClip model3 and Shore 2020.4 Although Armoiry and Connock state that in the UK ‘cost-effectiveness is a…



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