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Longitudinal fat fraction, liver stiffness may signal rapid progression in NAFLD



The temporal change rate of proton density fat fraction and liver stiffness measurement are promising predictors for those at high risk for rapid clinical progression and may improve patient management in those with nonalcoholic fatty liver disease.
“From our observation, at the early fibrosis stages, the rate of change of liver stiffness measurement (LSM) is slow and positively correlated with the rate of change in proton-density fat fraction (delta PDFF),” Meng Yin, MD, from Mayo Clinic, told Healio Gastroenterology. “At later fibrosis stages, the rate of change in LSM is

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