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EHS

New evidence of a preventative therapy for gout

Among patients with cardiovascular disease, it’s a common complaint: a sudden, piercing pain, stiffness or tenderness in a joint that lasts for days at a time with all signs pointing to a gout attack. Gout and cardiovascular disease (CVD) appear to be intimately linked—they are frequently seen together although the underlying connection between the two remains unclear. When rheumatologist Daniel Solomon, MD, MPH, heard about a large, clinical study to determine if targeting inflammation among patients with a history of heart attacks could lower future risk of cardiovascular events, he immediately wondered if the new approach might help prevent gout attacks among these patients as well. Solomon and colleagues found a significant reduction in risk of gout attacks among patients who received the drug that targets a key inflammatory molecule, suggesting a new target for therapeutic strategies to prevent gout attacks. Their findings are published online today in Annals of Internal Medicine.

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