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Study: Fidaxomicin ‘better’ option than vancomycin in many C. difficile cases

Based on a systematic review and network meta-analysis, researchers said fidaxomicin is a “better” option than vancomycin for the treatment of Clostridium difficile in all patients except those with severe infections and that metronidazole “should not be recommended” to treat the infection.
Venkataraman Subramanian, MD, clinical associate professor and honorary consultant gastroenterologist at the Leeds Institute of Biomedical and Clinical Studies in Leeds, England, and colleagues compared and ranked treatments for non-multiply recurrent C. difficile infections and
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