Advancements in MRI are giving us an unprecedented look at the fetal brain.
Until approximately a decade ago, what researchers knew about the developing prenatal brain came primarily from analyzing the brains of aborted or miscarried fetuses. But studying postmortem brains can be confounding because scientists can’t definitively pinpoint whether the injuries to the brain occurred before or during birth.
Over the years, however, improvements to MRI are finally enabling researchers to study the developing brain in real time. With these advancements, researchers are just beginning to understand how normal brains develop, and how abnormalities can manifest over the course of development. Scientists cataloguing typical infant brain development with the mini-MRI hope to use it eventually to study the brains of premature babies, who have a high risk of brain damage. Ultimately, clinicians hope to intervene early with therapies, if available and approved, to prevent developmental disorders when there are signs of brain damage in utero or shortly after birth.
Read more here in Nature Medicine.