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Effect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trial.

Effect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trial.

J Clin Periodontol. 2018 Jul 19;:

Authors: Quintero A, Chaparro A, Quirynen M, Ramirez V, Prieto D, Morales H, Prada P, Hernández M, Sanz A

Abstract
AIM: To evaluate the impact of two non-surgical periodontal treatment modalities on metabolic and periodontal clinical parameters in subjects with type 2 diabetes mellitus (T2DM) and poor glycaemic control and chronic periodontitis.
MATERIAL AND METHODS: A randomized controlled clinical trial was conducted. 93 T2DM subjects with glycosylated haemoglobin (HbA1c) > 7% were randomly assigned to one of two groups receiving scaling with root planing in multiple sessions quadrant by quadrant (Q by Q) or within 24 hours (one stage). Periodontal parameters, HbA1c, glycaemia blood levels (FPG) and C-reactive protein (CRP) values were assessed at baseline and at 3 and 6 months post-therapy.
RESULTS: At 6 months, HbA1c had decreased by 0.48% in the Q by Q group and by 0.18% in the one-stage group (p=0.455). After therapy, subjects with an initial HbA1c < 9% showed an increase of 0.31% (p=0.145), compared with a decrease of 0.88% (p=0.006) in those with an initial HbA1c ≥ 9%. Periodontal parameters improved significantly (p < 0.0001) post-therapy, with similar results for both treatment modalities.
CONCLUSION: Periodontal therapy had the greatest impact on HbA1c reduction on patients with an HbA1c > 9% regardless of treatment modality. Both modalities resulted in significant improvements in periodontal parameters. This article is protected by copyright. All rights reserved.

PMID: 30024030 [PubMed – as supplied by publisher]

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